The prevention of acute mountain sickness – the effect of theophylline and acetazolamide in prevention of acute mountain sickness
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منابع مشابه
Acetazolamide in prevention of acute mountain sickness: a double-blind controlled cross-over study.
Twenty-four amateur climbers took part in a double-blind controlled cross-over trial of acetazolamide versus placebo for the prevention of acute mountain sickness. They climbed Kilimanjaro (5895 m) and Mt Kenya (5186 m) in three weeks with five rest days between ascents. The severity of acute mountain sickness was gauged by a score derived from symptoms recorded daily by each subject. On kilima...
متن کاملIdentifying the lowest effective dose of acetazolamide for the prophylaxis of acute mountain sickness: systematic review and meta-analysis
OBJECTIVES To assess the efficacy of three different daily doses of acetazolamide in the prevention of acute mountain sickness and to determine the lowest effective dose. DESIGN Systematic review and meta-analysis. DATA SOURCES Medline and Embase along with a hand search of selected bibliographies. No language restrictions were applied. STUDY SELECTION Randomised controlled trials assessi...
متن کاملEfficacy and harm of pharmacological prevention of acute mountain sickness: quantitative systematic review.
OBJECTIVE To quantify efficacy and harm of pharmacological prevention of acute mountain sickness. DATA SOURCES Systematic search (Medline, Embase, Cochrane Library, internet, bibliographies, authors) in any language, up to October 1999. STUDY SELECTION Randomised placebo controlled trials. DATA EXTRACTION Dichotomous data on efficacy and harm from 33 trials (523 subjects received 13 diffe...
متن کاملRespiratory rate within the first hour of ascent predicts subsequent acute mountain sickness severity.
BACKGROUND Altitude illness results from hypobaric hypoxia at altitudes higher than 2500 meters above sea level. To determine whether vital signs can be used as predictors for severe acute mountain sickness, we carried out a prospective observational study. METHODS A cohort of 90 individuals (male/female ratio: 2; age: 13 - 65 years) in a mountain hotel's clinic at 3450 meters in Iran were st...
متن کاملGinkgo biloba and acetazolamide prophylaxis for acute mountain sickness: a randomized, placebo-controlled trial.
BACKGROUND Acute mountain sickness (AMS) commonly occurs when unacclimatized individuals ascend to altitudes above 2000 m. Acetazolamide and Ginkgo biloba have both been recommended for AMS prophylaxis; however, there is conflicting evidence regarding the efficacy of Ginkgo biloba use. We performed a randomized, placebo-controlled trial of acetazolamide vs Ginkgo biloba for AMS prophylaxis. M...
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تاریخ انتشار 2004